B.S. Biology, summa cum laude, College of William and Mary
M.A. Molecular Biology, Princeton University
Ph.D. Molecular Biology, Princeton University
Postdoctoral research, Biochemistry and Molecular Biology, Michigan State University
Concepts of Biology: Genes, Genomics, and Society (BIO 118)
Principles of Biology III: Cells and Molecules (BIO 152)
Biochemistry (BIO 220)
Genomes and Gene Evolution (BIO 485), with Dr. Bruce Wightman
Foods, Broods, and Moods: The Impact of Genetics on Society (FYS 236)
My scientific interests focus on the regulation of gene function; in particular, I am interested in how factors such as packaging of DNA into chromatin and DNA methylation may affect gene expression in eukaryotic organisms. One area of current research investigates the biological roles of proteins known to covalently modify chromatin structure in the model plant Arabidopsis thaliana. Students in my lab are also engaged in a comparative genomics project that uses in silico (computer-based) analysis to annotate genes in Drosophila species. This latter line of experimentation is a collaborative effort of the Genomics Education Partnership, which is supported by the Howard Hughes Medical Institute.
*denotes undergraduate co-author
Wightman, B. and Hark, A. T., 2012, Integration of Bioinformatics into an Undergraduate Biology Curriculum and the Impact on Development of Mathematical Skills, Biochemistry and Molecular Biology Education, 40(5): 310–319.
Cohen, R.*, J. Schocken*, A. Kaldis, K.E. Vlachonasios, A.T. Hark, and E.R. McCain. 2009. The histone acetyltransferase GCN5 affects the inflorescence meristem and stamen development in Arabidopsis. Planta 230: 1207-1221.
Hark, A.T., K.E. Vlachonasios, K.A. Pavangadkar, S. Rao, H. Gordon*, I.-D. Adamakis, A. Kaldis, M.F. Thomashow, and S.J.Triezenberg. 2009. Two Arabidopsis orthologs of the transcriptional coactivator ADA2 have distinct biological functions. Biochimica et Biophysica Acta 1789: 117-124.
Hark, A.T. 2008. Crossing over: An undergraduate service learning project that connects to biotechnology education in secondary schools. Biochemistry and Molecular Biology Education 36, 159-165.