Debra A. Walther
New Science Building, 003
B. S. Biological Sciences, University of Delaware
Ph.D. Genetics, University of Wisconsin-Madison
Postdoctoral Fellow, Brandeis University
Concepts of Biology: From DNA to Cancer (BIO 107)
Principles of Biology II Laboratory (BIO 151)
Principles of Biology III Laboratory (BIO 152)
My research interests are focused on understanding the mechanism of recombinational DNA repair using yeast as a model organism. I use chromosome tagging and fluorescence microscopy of living yeast cells to study the dynamics and nuclear arrangement of chromosomal loci involved in recombination. I am interested in understanding changes in chromosome dynamics in response to DNA damage through the development and application of new methods in fluorescence microscopy.
*denotes undergraduate co-author
(as D. Bressan)
Carlton P. M., J. Boulanger, C. Kervrann, J. B. Sibarita, J. Salamero, S. Gordon-Messer, D. Bressan, J. E. Haber, S. Haase, L. Shao, L. Winoto, A. Matsuda, P. Kner, S. Uzawa, M. Gustafsson, Z. Kam, D. A. Agard, and J. W. Sedat. 2010. Fast live simultaneous multiwavelength four-dimensional optical microscopy. Proc. Natl. Acad. Sci. U. S. A. 107(37): 16016-16022.